Length: 4. For this reason, we continued with the optimization of the reaction conditions using this enzyme. All experiments were carried out in duplicate. Generation of aptamers with an expanded chemical repertoire. Gold L. To whom correspondence should be addressed. We need to integrate the knowledge and skills from different disciplines and from communities all over the world to enable effective responses to future epidemics.
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Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis.
Skip to main content. Afterwards the oligonucleotides were lyophilized and resuspended in Milli-Q water. Park C.
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Nature Research menu. DryjaM. Combination therapy with the anti-HIV-1 monoclonal antibodies 3BNC and maintains long-term suppression in the absence of antiretroviral therapy in individuals with antibody-sensitive viral reservoirs.
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Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases. Marleen Renders, Shrinivas Dumbre, [.
A Schematic presentation of the modified nucleotides used in this study, 1a—fB the aryl R moieties in 1a—f. Fellouse F. Data were recorded using Octet Data Acquisition 8.
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MF3 came with a 5-speed manual transmission as basic, and a 6-speed sequential gearbox as an option. The nucleotide 1f was obtained from nucleotide 1e by transfer hydrogenolysis catalyzed by palladium on carbon in cyclohexene. Schermerhorn K.
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The control reaction in which the template strand is omitted, is shown in Supplementary Figure S4.
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Search Article search Search. Letter 27 March Open Access Mapping changes in housing in sub-Saharan Africa from to The prevalence of improved housing with improved drinking water and sanitation, sufficient living area and durable construction in urban and rural sub-Saharan Africa doubled between and Probing ambiguous base-pairs by genetic transformation with XNA templates.